Comparative transcriptome profiling of the human and mouse dorsal root ganglia: an RNA-seq–based resource for pain and sensory neuroscience research

P Ray, A Torck, L Quigley, A Wangzhou, M Neiman… - Pain, 2018 - journals.lww.com
… Our analyses reveal an hDRG-enriched protein-coding gene … nerve transcriptomes suggests
trafficking of neuronal mRNA to … and spinal cord with respect to the rest of the CNS. A third …

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation

KE Stephens, Z Chen, E Sivanesan, SN Raja… - Molecular …, 2018 - journals.sagepub.com
… repetitive spinal cord stimulation represses transcription of … To identify genes that were
differentially regulated following … Principal component analysis shows segregation of the …

… in Acute and Chronic Allodynia: Using Human Psychophysics, Sensory Analysis, Glial Modulation and Functional Proteomics in the Dorsal Horn of the Spinal Cord

S Shaikh - 2017 - search.proquest.com
tactile and cold allodynia arise when normal sensory traffic is … proteomic profiling, analyse
regulation of protein expression … ALE meta-analysis reveals dissociable networks for affective …

Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms …

Y Li, C Yin, B Liu, H Nie, J Wang, D Zeng… - Journal of …, 2021 - Springer
… and get involved in transcriptional modulation or regulating … The mechanical allodynia lasted
till the end of our … Astrocytes and microglia in spinal cord dorsal (SCDH) horn play important

RNA profiling of human dorsal root ganglia reveals sex differences in mechanisms promoting neuropathic pain

PR Ray, S Shiers, JP Caruso, D Tavares-Ferreira… - Brain, 2023 - academic.oup.com
… Our analysis reveals clear sex differences in sets of genes … spontaneous pain, hyperalgesia
or allodynia in a region at or … through this important transcriptional regulatory pathway. For …

Spared nerve injury causes sexually dimorphic mechanical allodynia and differential gene expression in spinal cords and dorsal root ganglia in rats

FHG Ahlström, K Mätlik, H Viisanen, KJ Blomqvist… - Molecular …, 2021 - Springer
… to be important in the induction of allodynia in female rats. … in females imply a divergent
change in transcription in DRG … Pathway and biological process analysis revealed, in particular, …

Analyses of long non-coding RNA and mRNA profiles in the spinal cord of rats using RNA sequencing during the progression of neuropathic pain in an SNI model

J Zhou, Y Fan, H Chen - RNA biology, 2017 - Taylor & Francis
… Both mechanical allodynia and thermal sensitivity were … lncRNAs regulate gene expression
and traffic cellular protein complexes, … Our analyses revealed complex network relationships …

Dorsal root ganglion transcriptome analysis following peripheral nerve injury in mice

S Wu, B Marie Lutz, X Miao, L Liang, K Mo… - Molecular …, 2016 - journals.sagepub.com
… L4 spinal nerve ligation produced mechanical allodynia in … play a key role in regulating the
transmission of peripheral … of kappa opioid receptors in spinal cord and DRG to vary with the …

[HTML][HTML] Rbfox1 regulates alternative splicing of Nrcam in primary sensory neurons to mediate peripheral nerve injury-induced neuropathic pain

L He, H Guo, H Wang, K Zhu, D Li, C Zhang, Y Ai… - …, 2024 - Elsevier
analysis of alternative RNA splicing in injured DRG following … GO analysis revealed several
biological processes … GFAP in the ipsilateral L 4 spinal cord dorsal horn could be inhibited by …

Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain

S Tansley, S Uttam, A Ureña Guzmán, M Yaqubi… - Nature …, 2022 - nature.com
… in lipid metabolism and trafficking and has been implicated in … This analysis revealed
associations between transcriptional … and 5 months after surgery to quantify mechanical allodynia. …